What is the characteristic feature of erythema multiforme?

Erythema multiforme is characterized by the presence of target lesions, which are distinctive, concentric rings of erythema surrounding a central area of darker coloration. These target lesions typically appear on the extremities and can also occur on the face and trunk. They are a significant clinical feature that allows healthcare providers to recognize and differentiate erythema multiforme from other skin conditions. The target lesions can vary in size and may be associated with other symptoms such as fever and malaise, but the unique appearance of the lesions themselves is what primarily identifies the condition.

Additionally, while bright-red macules, blisters, pustules, and pinpoint wheals may be seen in various dermatological conditions, they do not accurately represent the specific presentation of erythema multiforme. The presence of target lesions is specific and crucial for diagnosing this condition effectively.