What is the first-line treatment for cervicitis caused by Chlamydia trachomatis?

Cervicitis caused by Chlamydia trachomatis is most commonly treated with either azithromycin or doxycycline, making this the first-line treatment. Azithromycin 1g taken orally in a single dose is effective for uncomplicated gonococcal and chlamydial infections due to its potency and convenient dosing. Doxycycline, taken at 100mg twice daily for 10 days, is also effective and may be preferred in certain cases, particularly in situations where follow-up is a concern.

Chlamydia is the most prevalent sexually transmitted bacterium and can lead to significant complications if left untreated, particularly in reproductive health. The first-line treatments have been widely studied, demonstrating good efficacy in eradicating the infection and providing rapid relief of symptoms.

While amoxicillin may be effective for certain infections, it is not the first choice for chlamydia-related cervicitis. Ceftriaxone is typically used as a first-line treatment for gonorrhea and does not cover chlamydia unless given in conjunction with another antibiotic. Metronidazole is utilized for bacterial vaginosis or trichomoniasis but is not the appropriate choice for treating chlamydial infections, which is specifically what this question addresses.