What is the typical presentation on EGD for CMV esophagitis?

The typical presentation on esophagogastroduodenoscopy (EGD) for cytomegalovirus (CMV) esophagitis is characterized by large superficial ulcers. This finding is significant because CMV esophagitis often occurs in immunocompromised individuals, such as those with HIV/AIDS, organ transplant recipients, or patients on immunosuppressive therapy.

During the EGD, the large superficial ulcers can be visualized along the esophagus, and they may appear as well-defined, round lesions. These ulcers represent areas of necrosis where the virus has invaded the esophageal mucosa, leading to ulcer formation. This presentation contrasts with other conditions, like herpes simplex virus (HSV) esophagitis, which typically presents with smaller, more localized ulcers.

Recognizing this characteristic helps guide appropriate diagnosis and management, as CMV esophagitis is treated differently than other causes of esophagitis. Understanding these visual findings on EGD is crucial for medical professionals in the emergency medicine field and beyond, allowing for timely interventions in affected patients.