Which antidepressants are classified as SNRIs?

The classification of antidepressants into SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors) is critical for understanding their mechanism of action and therapeutic applications. SNRIs are designed to increase the levels of both serotonin and norepinephrine in the brain by inhibiting their reuptake at the synaptic cleft.

The correct answer includes Venlafaxine, Desvenlafaxine, and Duloxetine, all of which are well-established SNRIs.

Venlafaxine is commonly used for the treatment of major depressive disorder, anxiety disorders, and panic disorder, and as the dosage increases, it also targets norepinephrine reuptake more prominently. Desvenlafaxine is the active metabolite of Venlafaxine and functions similarly, providing an option for patients who may need an alternative form of treatment. Duloxetine is prescribed for depression as well as for generalized anxiety disorder and chronic pain conditions, taking advantage of its dual-action on serotonin and norepinephrine.

The other options include medications that do not fit the SNRI classification. For example, the first option mentions Sertraline and Fluoxetine, which are both SSRIs (Selective Serotonin Reuptake Inhibitors), only affecting