Which blood vessel is most commonly involved in anterior epistaxis?

Anterior epistaxis, or bleeding from the front part of the nose, is most commonly associated with Kiesselbach's plexus. This area, also known as Little's area, is a rich network of blood vessels located on the anterior portion of the nasal septum. It is particularly susceptible to trauma and irritation, which are common causes of nosebleeds.

When considering the other options, while the palatine artery, maxillary artery, and facial artery may contribute to nasal circulation, they are not typically the primary source of bleeding seen in anterior nosebleeds. Kiesselbach’s plexus stands out due to its anatomical position and the sheer number of small, superficial vessels it contains, making it more prone to rupture with minor trauma or dryness. In practice, most cases of anterior epistaxis will resolve after simple interventions directed at this site, validating its role as the most common source in these situations.