Which laboratory value is NOT typically elevated in cases of acute pancreatitis?

In acute pancreatitis, the laboratory values most commonly elevated include lipase, triglycerides, and liver enzymes such as AST and ALT. However, calcium levels do not typically rise in acute pancreatitis; in fact, they can often be low or normal.

Lipase is a key enzyme produced by the pancreas and is significantly elevated in cases of pancreatitis, making it a reliable biomarker for diagnosis. Triglycerides can also be elevated in acute pancreatitis, particularly in cases associated with hyperlipidemia, which is one of the common causes of this condition. Similarly, liver enzymes like AST and ALT may be elevated due to the close anatomical relation of the liver and pancreas, and the stress response associated with pancreatitis.

Calcium metabolism may be affected in various ways during severe cases of pancreatitis, often leading to hypocalcemia due to saponification of fat necrosis or other metabolic disturbances. It is crucial to recognize that while serum calcium can fluctuate in various pathological states, it is generally not elevated in the setting of acute pancreatitis, which makes it an appropriate choice in this context.