Which skin condition is most commonly treated with topical calcineurin inhibitors?

Topical calcineurin inhibitors, such as tacrolimus and pimecrolimus, are commonly used in the management of atopic dermatitis. This condition is characterized by chronic inflammation of the skin and is often associated with symptoms like itchy, red, and inflamed skin. Calcineurin inhibitors are particularly beneficial in atopic dermatitis as they help reduce inflammation and the immune response without the side effects associated with long-term use of topical corticosteroids, such as skin thinning.

The use of calcineurin inhibitors is especially valuable in sensitive areas such as the face and genital regions, where conventional steroids might lead to adverse effects if used over a prolonged period. Furthermore, these medications are safe for use in children and can be applied long-term, making them an important option in the management of atopic dermatitis.

While other skin conditions listed may involve inflammation or irritation, they are not typically treated with topical calcineurin inhibitors. For instance, lichen planus often requires corticosteroids or other systemic treatments, nummular eczema might be managed with topical steroids or moisturizers, and tinea versicolor, which is a fungal infection, is best treated with antifungal agents rather than anti-inflammatory therapies.